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Treatment
Stabilizing an adrenal crisis
An adrenal crisis requires emergency veterinary care. Treatment may include intravenous fluids, correction of dangerous electrolyte or blood-sugar abnormalities, supportive care, and prompt glucocorticoid replacement. The immediate goal is to restore circulation and stabilize the body's most urgent imbalances.
Long-term hormone replacement
Once a dog is stable, treatment is designed to replace the hormones the adrenal glands are no longer supplying adequately. Dogs with mineralocorticoid deficiency may receive a long-acting mineralocorticoid injection or an oral mineralocorticoid. Dogs also need glucocorticoid replacement, commonly with a corticosteroid prescribed by their veterinarian.
The exact medication, dose, and schedule are individualized. A dog with atypical Addison's may initially need glucocorticoid replacement alone, while some dogs later develop mineralocorticoid deficiency and require a change in treatment.
Monitoring is part of treatment
Addison's is generally a lifelong condition, so treatment does not end when a dog feels better. Veterinary rechecks and laboratory monitoring help determine whether hormone replacement is appropriate and whether medication needs to be adjusted. Owners should also watch for changes in appetite, energy, vomiting, diarrhea, drinking, urination, or weakness.
Stress and illness
Because cortisol helps the body respond to stress, a veterinarian may recommend temporarily increasing glucocorticoid support during significant illness, injury, surgery, or other stressful events. The plan should be established with the dog's veterinarian rather than adjusted independently.
Living well with Addison's
With appropriate treatment and monitoring, the long-term outlook for dogs with Addison's disease is generally good. The goal is not simply to control laboratory values—it is to help each dog remain comfortable, active, and able to enjoy life.